Thou should report this at Trend Micro. MS has no control over their poorly designed AV product.
I use ESET and never had any problems. MS testlabs also uses ESET, at least they did in the past. 
Malwarebytes is an extremely well additional second opinion scanner which could be used as AV product too. The same for a product like Spybot Search & Destroy.
Malwarebytes is an typical USA product. Spybot and ESET are European products, German and Slovakian.
Guess this āSomebodyā has to be me lol.
Anyway, thanks for the help!
I am not able to get rid of this error. My antivirus (Bitdefender) is in game mode, the game is whitelisted in firewall and antivirus. Somethimes it occours inside a match.
You could always try it a while without additional AV scanner or using the MalwareBytes free download for a second opinion scan, but there also could be something else wrong.
Did you also enable Windows game mode? Press Win + G inside the game to check if it is enabled.
Looks like the problem was really the Bitdefender. Only with AntimalwareBytes the game worked fine. I see it is having problems with not only one AV. Maybe Microsoft could look better at this.
AOE DE (and many other store games too) have problems with third party AV programs except for just a few brands. Itās not a problem of the game nor MS. The culprit is about the way the AV application is designed. Depending on the AV application in use more steps may be required of course to get it running smoothly. Personally I donāt know all exclusion options available in Bitdefender, maybe you missed some.
I found the problem, I had to list the WindowsApps directory available to my user without asking for admin privileges, so Bitdefender was able to find the executable and whitelist. But the default permissions for WindowsApps directory make it a lot difficult for most users.
Thanks for reporting back that about Bitdefender. Itās indeed not easy to get that path for most users and it changes after a version update. Excluding the whole WindowsApps folder including subfolders would cause big security risks btw, so I would never do that.
I did this yet it still happens to me. I play it on steam.
Same problem here, downloaded by Steam. In white list of Firewall of Bitdefender and still not working
From Beta to Alfa and still didnāt solve the problem?
I bought the game on Steam today. I am also having this issue. I do not have Trend Micro. I am using AVG and have the application allowed etc through the firewall etc.
I wanted to stream some game-play and so I do have other applications open, but I wouldnāt think they would be stopping the game from running.
Also this problem with bitdefender
i disabled bitdef and windows defender also the firewall and still doesnt work, with only basic processes active (razer, nvidia, audio) and still doesnt work. The time for the error depends, sometimes it closes in one minute, sometimes i reach tool age
i tried playing 20 times but i guess i gotta stick to the old game
i have no idea what to do, also whitelisted the windowsapps but nothing works
Same problem here with bitdefender.
Step one:
Could it be two processes?
It also could be caused by other running background services like NVidia Shadow Play and NVidia Streaming services Iāve read somewhere on the internet.
Two things:
Are you a developer? If not do developers read this or where can I contact them?
Second:
I think MS made a big mistake lunching a game like this untested in the real world. The AOE community is trying its best to get a revival going and bad reviews like the ones on steam are hurting thisin a major way. If AOE DE is to be the new competitive strategy game (eg SC2 killer) they sure should try a bit harder in my opinion.
I also have this same problem with Bit Defender. Everything worked fine until this new update.
Iāve got nothing running in the background, Iāve managed to get the Threat defense to exclude the exe, same in the firewall. Permissions are all changed, drivers updatedā¦ I donāt know what else to do
No, happily Iām not, but they do read on this forum. Well, at least the staff is.
There is a bug section where you can report things like this.
https://forums.ageofempires.com/c/age-of-empires-definitive-edition/aoe-de-bugs
It got more complicated to troubleshoot the paths as there are now two versions, the MS store version and Steam version. So at least that difference should be taken into account. The support page does notice the path.
With the store version the path changes after each major update, so you need to correct it again, through a PowerShell command you can get and copy that new path again. Regarding the Steam version I donāt know how it works there, because I donāt own the game there.
Where people work mistakes happen. I agree they really gave it a short time of testing, but they will get it right again like before.
@TheRealNiQuil @Heat3999 @CallingSpice993 @LupaWolf152 @ThorKowlaska Thank you all for following up here! As @PCS70 has noted, the most common reason for the error you are experiencing is due to your antivirus or firewall blocking the game from running properly; you should be able to work around the problem by adding your Age of Empires game executable to your programās white-list.
This solution seems to work for most people, though Iām very interested if that is not the case for any of you. Hereās a few questions you can answer for me:
The team is working on a permanent fix for the problem now, though let me know if you want to explore other steps to see if we can narrow this down before that point.
Thanks for your patience; let me know what you have tried so I can continue to follow up with the team!
I was fairly certain that this is an error running with a game overlay for me. I am not using an AV software and the game is whitelisted on my firewall. After disabling the windows game bar it seemed to at least let me play for a few minutes before getting the error but it did still happen. 
Yes. Thatās exactly what Iām talking about. There are more processes or game overlay apps that could interfere with AOE DE except for antivirus and firewall apps. It would be useful if at least the AOE DE error screen is more specific about the process that it detects and causes problems.