CTD when launching a game in Full Desktop

I have three monitors and would love to run the game across all three. I have a powerful enough graphics card (RTX 3090), a 16-core processor (Ryzen 9 5950x), and 64 GB of 3200 MHz DDR4 RAM. However, the game crashes as soon as I launch a campaign or skirmish game. All of my hardware has up-to-date drivers, and I am running an up-to-date Windows 10 Pro OS. I should add that 2 of my monitors are QHD (2560x1440p) and the main one I use is a WQHD (3440x1440p) resolution. All three are gaming monitors that are Gsync or Gsync compatible.

I’ve tried numerous times to enable full desktop over many days, so I know it is not a temporary issue.